Some Properties and Major Functions of Plasma Proteins
|
Plasma protein components |
Major functions |
|
Total proteins |
Nutritive, transport,
osmotic pressure: buffer, defence, blood coagulation. |
|
1. Pre -
albumin Albumin |
Transport of
some thyroxine. Nutritive,
transport, osmotic, buffer |
|
2. Total
globulins |
|
|
alpha 1 -
globulins |
|
|
alpha1-glycoprotein
|
(Inhibitor of
trypsin) |
|
alpha1 -
lipoproteins (HDL) |
Transport of
phospholipids and cholesterol. |
|
Thyroxine binding
globulin |
Binds and
transports thyroid hormones |
|
alpha 2 -
globulins |
|
|
alpha2-
glycoproteins |
|
|
alpha2-
macroglobulin |
antiplasmin
and anti-trypsin activity. |
|
Haptoglobins |
Binds free
haemoglobin and prevents its excretion: peroxidase action. |
|
Prothrombin |
Forms thrombin
during blood coagulation |
|
Ceruloplasmin |
Copper
transport. Oxidation of Fe2+ to Fe3+ |
|
Beta
-globulins |
|
|
beta-1
Lipoproteins (LDL) (d 0.98 -1.03) |
Transports triglycerides, cholesterol, and Phospholipids. |
|
3. Transferrin
(siderophilin) |
Transport of
Fe3+ |
|
4. Plasminogen
(Profibrinolysin) |
Forms plasmin
for fibrinolysis |
|
5. Fibrinogen |
Blood
coagulation |
|
6. gamma-Globulin (Immunoglobulins) |
|
|
a) IgG |
Antibody
functions |
|
b) IgA |
Antibody
functions |
|
c) IgM |
Antibody
functions |
